Xiangtian Zhou Selected Research

Myopia

9/2022	Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia.
1/2022	Dysfunction of VIPR2 leads to myopia in humans and mice.
1/2022	Form-deprivation myopia downregulates calcium levels in retinal horizontal cells in mice.
1/2022	Retinal Dopamine D2 Receptors Participate in the Development of Myopia in Mice.
1/2022	Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice.
12/2021	Decreased Choroidal Blood Perfusion Induces Myopia in Guinea Pigs.
11/2021	Declines in PDE4B activity promote myopia progression through downregulation of scleral collagen expression.
10/2021	Dietary ω-3 polyunsaturated fatty acids are protective for myopia.
1/2021	Canonical Wnt Signaling Drives Myopia Development and Can Be Pharmacologically Modulated.
1/2021	PDE4B Proposed as a High Myopia Susceptibility Gene in Chinese Population.

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Xiangtian Zhou Research Topics

Disease

50	Myopia 09/2022 - 04/2006
7	Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy) 01/2020 - 03/2005
6	Hypoxia (Hypoxemia) 01/2022 - 01/2018
5	Refractive Errors (Refractive Error) 01/2020 - 03/2009
4	Mitochondrial Diseases (Mitochondrial Disease) 11/2011 - 02/2006
3	Hyperopia (Hypermetropia) 01/2020 - 04/2007
3	Body Weight (Weight, Body) 01/2020 - 08/2014
3	Melanoma (Melanoma, Malignant) 08/2013 - 11/2007
3	Uveal melanoma 01/2011 - 11/2007
2	Neoplasms (Cancer) 01/2022 - 04/2009
2	Dry Eye Syndromes (Dry Eye Syndrome) 11/2018 - 11/2015
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2022
1	Amphetamine-Related Disorders (Addiction, Amphetamine) 07/2020
1	Fibrosis (Cirrhosis) 01/2020
1	Myopia 1 11/2017
1	Mydriasis 01/2017
1	Infections 01/2017
1	Ganglion Cysts (Ganglion) 04/2016
1	Degenerative Myopia 09/2014
1	Albinism 09/2014

Drug/Important Bio-Agent (IBA)

16	Retinaldehyde (Retinal)IBA 09/2022 - 06/2011
9	CollagenIBA 01/2022 - 09/2010
8	Dopamine (Intropin)FDA LinkGeneric 09/2022 - 09/2014
6	Mitochondrial DNA (mtDNA)IBA 02/2016 - 03/2005
5	Proteins (Proteins, Gene)FDA Link 12/2021 - 11/2007
4	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2022 - 08/2014
4	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 05/2010
4	Apomorphine FDA Link 11/2020 - 09/2014
4	Messenger RNA (mRNA)IBA 01/2020 - 11/2007
4	Dopamine Agonists (Dopamine Agonist)IBA 01/2018 - 01/2011
3	Sulpiride (neogama)IBA 01/2022 - 08/2014
3	Pharmaceutical PreparationsIBA 12/2021 - 01/2018
3	QuinpiroleIBA 12/2021 - 09/2014
3	Dopamine D1 Receptors (Dopamine D1 Receptor)IBA 01/2018 - 01/2017
3	Transfer RNA (tRNA)IBA 06/2007 - 02/2006
2	Indicators and Reagents (Reagents)IBA 01/2022 - 11/2018
2	pimonidazoleIBA 12/2021 - 11/2020
2	Adenosine Monophosphate (AMP)IBA 11/2021 - 01/2020
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2021 - 12/2018
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 04/2016
2	Collagen Type I (Type I Collagen)IBA 01/2021 - 01/2018
2	LigandsIBA 07/2020 - 02/2008
2	ProstaglandinsIBA 01/2020 - 09/2018
2	Monophenol Monooxygenase (Tyrosinase)IBA 01/2018 - 11/2007
2	Dopamine Receptors (Dopamine Receptor)IBA 01/2018 - 01/2017
2	Biological ProductsIBA 11/2017 - 01/2011
2	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 01/2011 - 09/2010
2	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 03/2009 - 04/2006
2	milk-derived factorIBA 04/2007 - 04/2006
1	MelatoninIBA 09/2022
1	Neurotransmitter Agents (Neurotransmitter)IBA 09/2022
1	CalciumIBA 01/2022
1	Hypoxia-Inducible Factor 1IBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 12/2021
1	EnzymesIBA 11/2021
1	RolipramIBA 11/2021
1	Eicosapentaenoic AcidIBA 10/2021
1	Docosahexaenoic AcidsIBA 10/2021
1	Therapeutic UsesIBA 10/2021
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 10/2021
1	alpha 1 Chain Collagen Type IIBA 01/2021
1	Niclosamide FDA Link 01/2021
1	Prazosin (Minipress)FDA LinkGeneric 11/2020
1	Atropine FDA LinkGeneric 11/2020
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2020
1	butaprostIBA 01/2020
1	6-isopropoxy-9-oxoxanthene-2-carboxylic acidIBA 01/2020
1	Green Fluorescent ProteinsIBA 01/2020
1	PPAR alphaIBA 01/2020
1	Aripiprazole (Abilify)FDA Link 01/2020
1	Adenosine Triphosphatases (ATPase)IBA 01/2020
1	Chemotactic FactorsIBA 01/2020
1	Clodronic Acid (Clodronate)IBA 01/2020
1	ChemokinesIBA 01/2020
1	Fibric Acids (Fibrates)IBA 12/2018
1	GW 7647IBA 12/2018
1	GW 6471IBA 12/2018
1	MucinsIBA 11/2018
1	prostaglandin F2alpha receptorIBA 09/2018
1	Adenine NucleotidesIBA 01/2018
1	RNA (Ribonucleic Acid)IBA 01/2018
1	formononetinIBA 01/2018
1	kojic acidIBA 01/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	rhodiolosideIBA 01/2018
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2018
1	Peptide Hydrolases (Proteases)FDA Link 01/2018
1	Cyclopentolate (Cyclogyl)FDA LinkGeneric 01/2017
1	Glucose (Dextrose)FDA LinkGeneric 01/2017
1	LipidsIBA 01/2017
1	Muscarinic AntagonistsIBA 01/2017
1	Tyrosine-tRNA LigaseIBA 02/2016
1	NeuropeptidesIBA 11/2015
1	Pilocarpine (Ocusert)FDA LinkGeneric 01/2015
1	2,3,4,5- Tetrahydro- 7,8- dihydroxy- 1- phenyl- 1H- 3- benzazepine (SKF 38393)IBA 09/2014
1	Dopamine Agents (Dopaminergic Agents)IBA 09/2014

Therapy/Procedure

4	Injections 12/2021 - 12/2013
2	Laser In Situ Keratomileusis (LASIK) 11/2018 - 11/2015
2	Lenses 01/2014 - 06/2009
1	Contact Lenses 01/2017